학술논문
Pruritus in Black Skin: Unique Molecular Characteristics and Clinical Features
Document Type
Article
Author
Source
Journal of the National Medical Association; February 2021, Vol. 113 Issue: 1 p30-38, 9p
Subject
Language
ISSN
00279684; 19434693
Abstract
Chronic pruritus dramatically disrupts quality of life, impairs sleep, and is difficult to treat. The pathogenesis and severity of chronic itch can vary significantly with race. Black skin has inherent structural and molecular characteristics that exacerbates pruritus, leading to unique presentations of pruritic conditions and added challenges in finding effective therapies. The aim of this review is to discuss structural variances in black skin, the subsequent epidemiological disparities in chronic pruritic conditions, and clinical management pearls for the management of itch in black patients.