학술논문
O-4 MBOAT7 RS641738 IS ASSOCIATED WITH PROGRESSION TO CIRRHOSIS IN NON-ALCOHOLIC FATTY LIVER DISEASE IN LATIN AMERICA
Document Type
Article
Author
Source
Annals of Hepatology; February 2024, Vol. 29 Issue: 1, Number 1 Supplement 1
Subject
Language
ISSN
16652681
Abstract
Latin Americans experience some of the highest global rates of non-alcoholic fatty liver disease (NAFLD) and the prevalence of cirrhosis is increasing in this population. The rs641738 C>T single nucleotide polymorphism (SNP) of MBOAT7 has been associated with NAFLD development and cirrhosis in Europeans with NAFLD. However, the impact of this SNP in Latin Americans is unclear. We aimed to evaluate a cohort of Latin Americans with NAFLD to determine if MBOAT7 effects the risk of cirrhosis in this understudied population.