학술논문
A prospective study to assess the association between genotype, phenotype and Prakritiin individuals on phenytoin monotherapy
Document Type
Article
Author
Source
Journal of Ayurveda and Integrative Medicine; January-March 2017, Vol. 8 Issue: 1 p37-41, 5p
Subject
Language
ISSN
09759476; 09762809
Abstract
Genetic polymorphisms in drug metabolizing enzymes (DMEs) impart distinct drug metabolizing capacity and a unique phenotype to an individual. Phenytoin has large inter-individual variability in metabolism due to polymorphisms in CYP2C9 and CYP2C19. As per Ayurveda, Prakritiimparts a unique phenotype to an individual.