학술논문
Prevalence and clinical associations of Staphylococcus aureussmall-colony variant respiratory infection in children with cystic fibrosis (SCVSA): a multicentre, observational study
Document Type
Article
Author
Wolter, Daniel J; Onchiri, Frankline M; Emerson, Julia; Precit, Mimi R; Lee, Michael; McNamara, Sharon; Nay, Laura; Blackledge, Marcella; Uluer, Ahmet; Orenstein, David M; Mann, Michelle; Hoover, Wynton; Gibson, Ronald L; Burns, Jane L; Hoffman, Lucas R; Wolter, Daniel J; Onchiri, Frankline M; Emerson, Julia; Precit, Mimi R; Lee, Michael; McNamara, Sharon; Nay, Laura; Blackledge, Marcella; Uluer, Ahmet; Orenstein, David M; Mann, Michelle; Hoover, Wynton; Gibson, Ronald L; Burns, Jane L; Qin, Xuan; Buccat, Anne Marie; Genatossio, Alan; Schaap, Nicoline; Lopez, Omalee; Doan, Kathy; Fowler, Robert; Iken, Khadija; Little, Kelsey; Hartigan, Elizabeth; Little, Kathryn; Hathorne, Heather; Keeling, Susan; Slaten, Katie; Hoffman, Lucas R
Source
The Lancet Respiratory Medicine; December 2019, Vol. 7 Issue: 12 p1027-1038, 12p
Subject
Language
ISSN
22132600; 22132619
Abstract
Staphylococcus aureusis the bacterium cultured most often from respiratory secretions of people with cystic fibrosis. Both meticillin-susceptible S aureusand meticillin-resistant S aureus(MRSA) can adapt to form slow-growing, antibiotic-resistant isolates known as small-colony variants that are not routinely identified by clinical laboratories. We aimed to determine the prevalence and clinical significance of S aureussmall-colony variants and their subtypes among children with cystic fibrosis.