학술논문
Experiments directed towards the synthesis of anthracyclinones. VIII. Functionalization of hydroxyanthraquinones by reductive Claisen rearrangements
Document Type
Article
Author
Source
Australian Journal of Chemistry; 1984, Vol. 37 Issue: 7 p1511-1529, 19p
Subject
Language
ISSN
00049425; 14450038
Abstract
Gentle heating of allyloxyanthraquinones with sodium dithionite in dimethylformamide/water effects a rapid and controlled rearrangement to give high yields of 2-allylhydroxyanthraquinones.Starting from quinizarin, key intermediates for two synthetic routes to 4-demethoxydaunomycinone have been prepared from products by means of two such reductive Claisen rearrangements.