학술논문
The efficacy of nifedipine and acebutolol in coronary artery disease assessed by radionuclide ventriculography
Document Type
Article
Source
Cardiovascular Drugs and Therapy; June 1989, Vol. 3 Issue: Supplement 1 p287-293, 7p
Subject
Language
ISSN
09203206; 15737241
Abstract
Summary The efficacy of a fixed combination of 10 mg nifedipine and 100 mg acebutolol was tested in 21 patients with angiographically proven coronary artery disease (CAD). Ejection fraction (EF), emptying and filling rate (VS and VD), and end-systolic volume (ESV) were assessed by means of radionuclide ventriculography at rest and during exercise prior to as well as 1 hour and 5 hours following oral drug application. Whereas exercise-induced worsening of cardiac function had been documented in all the patients prior to medication, EF and ESV improved significantly after drug administration.