학술논문
A systematic review and meta-analysis of sample size methodology for traumatic hemorrhage trials
Document Type
Article
Author
Source
Journal of Trauma and Acute Care Surgery; June 2023, Vol. 94 Issue: 6 p870-876, 7p
Subject
Language
ISSN
21630755; 21630763
Abstract
We review trauma hemorrhage RCTs and sample size determination. 13 trauma RCTs were included, 11 studies had negative results. Current methodology is limited by imprecise risk estimates, overly optimistic treatment effect size and lack of justification for treatment targets. @jamieghossein; @shanfernands; bram_rochwerg; kinabamd; @trauma_surgeon; #OttawaHospital