학술논문
Improvements of cognitive functions in mice heavily infected by Angiostrongylus cantonensisafter treatment with albendazole, dexamethasone, or co-therapy
Document Type
Article
Author
Source
Journal of Microbiology, Immunology and Infection; 20220101, Issue: Preprints
Subject
Language
ISSN
16841182
Abstract
Angiostrongylus cantonensis, the causative agent of human eosinophilic meningitis and eosinophilic meningoencepalitis, has been reported to cause cognitive impairments in the host. To determine whether drug treatment improves the cognitive functions, BALB/c mice infected with 50 third-stage larvae were treated with albendazole, dexamethasone, or co-therapy since day 7 or 14 post-infection for one or two weeks. Abilities of spatial memory and learning of these animals were assessed with the Morris water maze.