학술논문

Borreliacidal OspC Antibody Response of Canines with Lyme Disease Differs Significantly from That of Humans with Lyme Disease
Document Type
Article
Source
Clinical and Vaccine Immunology (formerly CDLI); May 2007, Vol. 14 Issue: 5 p635-637, 3p
Subject
Language
ISSN
15566811; 1556679X
Abstract
ABSTRACTHumans reliably produce high concentrations of borreliacidal OspC antibodies specific for the seven C-terminal amino acids shortly after infection with Borrelia burgdorferi. We show that dogs also produce OspC borreliacidal antibodies but that their frequencies, intensities, and antigenicities differ significantly. The findings therefore confirm a major difference between the borreliacidal antibody responses of humans and canines with Lyme disease.