학술논문

Calcium-binding protein from mouse Ehrlich ascites-tumour cells is homologous to human calcyclin
Document Type
Article
Source
Biochemical Journal; November 1989, Vol. 263 Issue: 3 p951-956, 6p
Subject
Language
ISSN
02646021; 14708728
Abstract
A Ca2+-binding protein was purified from mouse Ehrlich ascites-tumour cells. The protein forms monomers and disulphide-linked dimers, which can be separated by reverse-phase h.p.l.c. A partial amino acid sequence analysis demonstrated that the protein has an EF-hand structure. A striking homology was found to rat and human calcyclin (a member of the S-100 protein family), which is possibly involved in cell-cycle regulation.