학술논문
NFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation
Document Type
Article
Author
Source
Molecular Biology of the Cell; June 2016, Vol. 27 Issue: 11 p1712-1727, 16p
Subject
Language
ISSN
10591524; 19394586
Abstract
NFκB is a master regulator of protein quality control. It helps the cells to survive proteotoxicity by modulating autophagy via up-regulation of BAG3 and HspB8 expression, a molecular mechanism relevant to protein conformational diseases.