학술논문
Plasmid Incidence Rate and Conjugative Chloramphenicol and Tetracycline Resistance Plasmids in Malaysian Isolates of Salmonella typhi
Document Type
Article
Source
Microbiology and Immunology; February 1991, Vol. 35 Issue: 2 p157-161, 5p
Subject
Language
ISSN
03855600; 13480421
Abstract
Seven (6.1%) of 115 strains of Salmonella typhiisolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid‐bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coliK12 at frequencies from 1.6 × 10−7to 1.9 × 10−6. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.