학술논문

Toxicity, bioconcentration, and metabolism of the herbicide propanil (3′,4′-dichloropropionanilide) in freshwater fish
Document Type
Article
Source
Archives of Environmental Contamination and Toxicology; March 1983, Vol. 12 Issue: 2 p175-182, 8p
Subject
Language
ISSN
00904341; 14320703
Abstract
Fathead minnows (Pimephales promelas) were exposed to technical grade propanil (3',4'-dichloropropionanilide) in a flow-through diluter system to determine acute lethality. LC50 values were 11.5, 10.2, 8.6, and 3.4 mg·L-1 at 24, 48, 96, and 192 hr, respectively. Eggs, newly hatched fry, and juvenile fish of this species were similarly exposed but at lower concentrations and for a period of 58 days. The 58-day “no effect” concentration was between 0.4 and 0.6?g·L-1, based upon the physiological parameters of length and dry weight of juvenile fish.14C-Propanil did not bioconcentrate significantly in fathead minnows (1.6× for parent propanil in whole body). Rainbow trout (Salmo gairdneri) readily metabolized propanil, forming at least ten products. One metabolite recovered from trout bile was identified as either 3',4'-dichloro-2-hydroxypropionanilide or 3',4'-dichloro-3-hydroxy-propionanilide. The technical grade propanil also contained 0.67 mg·g-1 of 3,3',4,4'-tetrachloroazobenzene as a contaminant.