학술논문
Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection
Document Type
Article
Author
Source
Nature Chemical Biology; December 2016, Vol. 12 Issue: 12 p1037-1045, 9p
Subject
Language
ISSN
15524450; 15524469
Abstract
A metabolomics analysis finds that host glycolysis, fatty acid oxidation, the urea cycle, cholesterol biosynthesis and oxidative phosphorylation are modified by hepatitis C virus infection. These effects are mediated through nuclear receptor transcription factors HNF4α, PPARα and FXR.