학술논문
Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial
Document Type
Article
Author
Krown, Susan E; Moser, Carlee B; MacPhail, Patrick; Matining, Roy M; Godfrey, Catherine; Caruso, Stephanie R; Hosseinipour, Mina C; Samaneka, Wadzanai; Nyirenda, Mulinda; Busakhala, Naftali W; Okuku, Fred M; Kosgei, Josphat; Hoagland, Brenda; Mwelase, Noluthando; Oliver, Vincent O; Burger, Henriette; Mngqibisa, Rosie; Nokta, Mostafa; Campbell, Thomas B; Borok, Margaret Z; Moses, Agnes; Kanyama, Cecilia; Mukwekwerere, Pamela; Gudza, Ivy; Chauwa, Felluna; Ulaya, Godwin; Kutto, Irene; Cheruiyot, Priscilla; Okello, Clement; Nakaganda, Annet; Koskei, Geoffrey; Keter, Winnie; Netto, Juliana; Baião, Tamiris; Govender, Iveshni; O'Connell-Maritz, Jessica; Cain, Kevin; Okanda, John; Cornelissen, Lynne; Van Schalkwyk, Marije; Sikhosana, Rejoice; Ngcobo, Minenhle; Lee, Jeannette Y.; Harrison, Taylor; Wachsman, William; Shin, Katherine; Evans, Scott; Rothenberg, Jennifer; Hosey, Lara; McCarthy, Sean; Martinez-Maza, Otoniel; Rinaldo, Charles; Dittmer, Dirk; Rinaldo, Charles; Fletcher, Courtney; Rudek, Michelle; Asmelash, Aida; Hughes, Valery; Schouten, Jeffrey; Shugarts, David; Kujinga, Tapiwanashe; Zadzilka, Amanda; Kerui, Fredrick; Robertson, Debora; Rooney, James; Sewal, Krishna; Gottshall, Brian
Source
The Lancet; April 2020, Vol. 395 Issue: 10231 p1195-1207, 13p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Optimal treatment regimens for AIDS-associated Kaposi sarcoma, a frequent contributor to morbidity and mortality among people with HIV, have not been systematically evaluated in low-income and middle-income countries, where the disease is most common. In this study, we aimed to investigate optimal treatment strategies for advanced stage disease in areas of high prevalence and limited resources.