부산대학교 도서관

All positive blood culture isolates from a hematology unit, between 1991 and 1992, were evaluated retrospectively. A total of 88 bacteremic episodes (105 pathogens) were recorded. Patient population consisted of 31 males and 17 females and their age ranged from 17 to 78 years (median 57). 24/48 (50%) pts had 1 bacteremic episode, 12 (25%) pts had 2 episodes, 8 (17%) pts had 3 episodes and 4 (8%) pts had 4 episodes. Nearly all pts suffered from hematologic malignanci Fever <38°C was present in 78/88 (88.6%) cases. Severe Neutropema was present in 64/88 (72%) cases. Gram-positive bacteria were isolated in 64 (61%) cases, Gram-negative in 37 (35.2%), and others in 4 (3.8%) [l Bacillus, 1 Listeria, 1 Bacteroides, 1 Candida]. A total of 10 pts had died within 3 weeks of first positive blood culture. Of these fatal cases, Gram-negative bacteria were isolated in 8 episodes, Gram-positive in 5, and Candida in 1 (3 polymicrobial isolates). Among them, Pseudomonas aerug. (3 cases) and E. coli (3 cases) were the most prevalent. In conclusion, although Gram-positive bacteremias are increasing steadily (61% versus 40% during 1988–89 in the same unit), Gram-negative infections proved acting as main contributing factor for fatal bacteremias.