학술논문

Recommendation for Cardiac Magnetic Resonance Imaging-Based Phenotypic Study: Imaging Part
Document Type
Article
Source
Phenomics; 20210101, Issue: Preprints p1-20, 20p
Subject
Language
ISSN
2730583X; 27305848
Abstract
Cardiac magnetic resonance (CMR) imaging provides important biomarkers for the early diagnosis of many cardiovascular diseases and has been reported to reveal phenome-wide associations of cardiac/aortic structure and functionality in population studies. Nevertheless, due to the complexity of operation and variations among manufactural vendors, magnetic field strengths, coils, sequences, scan parameters, and image analysis approaches, CMR is rarely used in large cohort studies. Existing guidelines mainly focused on the diagnosis of cardiovascular diseases, which did not aim to basic research. The purpose of this study was to propose a recommendation for CMR based phenotype measurements for cohort study. We classify the imaging sequences of CMR into three categories according to the importance and universality of corresponding measurable phenotypes. The acquisition time and repeatability of the phenotypic measurement were also taken into consideration during the categorization. Unlike other guidelines, this recommendation focused on quantitative measurement of large amount of phenotypes from CMR.