학술논문
An idiotypic network model of AIDS immunopathogenesis.
Document Type
Article
Author
Source
Proceedings of the National Academy of Sciences of the United States of America; April 1991, Vol. 88 Issue: 8 p3060-3064, 5p
Subject
Language
ISSN
00278424; 10916490
Abstract
Considerations from a network theory of the immune system suggest that human immunodeficiency virus and allogeneic stimuli may act synergistically to cause AIDS. The immune responses to these stimuli include two components that are directed against each other. In some AIDS risk groups other antigens that mimic major histocompatibility complex antigens may substitute for allogeneic stimuli. Implications for the prevention of AIDS are discussed.