학술논문
The clinical and imaging features of FLNApositive and negative periventricular nodular heterotopia
Document Type
Article
Author
Source
Biomedical Journal; June 2022, Vol. 45 Issue: 3 p542-548, 7p
Subject
Language
ISSN
23194170; 23202890
Abstract
Periventricular nodular heterotopia (PVNH) is caused by abnormal neuronal migration, resulting in the neurons accumulate as nodules along the surface of the lateral ventricles. PVNH often cause epilepsy, psychomotor development or cognition problem. Mutations in FLNA(Filamin A) is the most common underlying genetic etiology. Our purpose is to delineate the clinical and imaging spectrum that differentiates FLNA-positive and FLNA-negative PVNH patients.