학술논문
CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease
Document Type
Article
Author
Mariani, Laura H.; Bomback, Andrew S.; Canetta, Pietro A.; Flessner, Michael F.; Helmuth, Margaret; Hladunewich, Michelle A.; Hogan, Jonathan J.; Kiryluk, Krzysztof; Nachman, Patrick H.; Nast, Cynthia C.; Rheault, Michelle N.; Rizk, Dana V.; Trachtman, Howard; Wenderfer, Scott E.; Bowers, Corinna; Hill-Callahan, Peg; Marasa, Maddalena; Poulton, Caroline J.; Revell, Adelaide; Vento, Suzanne; Barisoni, Laura; Cattran, Dan; D’Agati, Vivette; Jennette, J. Charles; Klein, Jon B.; Laurin, Louis-Philippe; Twombley, Katherine; Falk, Ronald J.; Gharavi, Ali G.; Gillespie, Brenda W.; Gipson, Debbie S.; Greenbaum, Larry A.; Holzman, Lawrence B.; Kretzler, Matthias; Robinson, Bruce; Smoyer, William E.; Guay-Woodford, Lisa M.; Ahn, Wooin; Appel, Gerald B.; Babayev, Revekka; Batal, Ibrahim; Bomback, Andrew S.; Brown, Eric; Campenot, Eric S.; Canetta, Pietro; Carlassara, Lucrezia; Chan, Brenda; Chatterjee, Debanjana; D’Agati, Vivette D.; Delbarba, Elisa; Dogra, Samriti; Fernandez, Hilda; Foroncewicz, Bartosz; Gharavi, Ali G.; Ghiggeri, Gian Marco; Hines, William H.; Ali Husain, S.; Jain, Namrata G.; Khairallah, Pascale; Kil, Byum Hee; Kiryluk, Krzysztof; Jeyabalan, Anushya; Lau, Wai L.; Lin, Fangming; Lugani, Francesca; Marasa, Maddalena; Markowitz, Glen; Mohan, Sumit; Mu, Xueru; Mucha, Krzysztof; Nickolas, Thomas L.; Piva, Stacy; Radhakrishnan, Jai; Rao, Maya K.; Regunathan-Shenk, Renu; Sanna-Cherchi, Simone; Santoriello, Dominick; Shirazian, Shayan; Stokes, Michael B.; Yu, Natalie; Valeri, Anthony M.; Zviti, Ronald; Greenbaum, Larry A.; Smoyer, William E.; Al-Uzri, Amira; Ambruzs, Josephine; Ashoor, Isa; Aviles, Diego; Baracco, Rossana; Barcia, John; Bartosh, Sharon; Belsha, Craig; Bowers, Corinna; Braun, Michael C.; Cai, Yi; Chernitskiy, Vladimir; Chishti, Aftab; Claes, Donna; Clark, Kira; Cramer, Carl; Davis, Keefe; Dutcher, Amy; Erkan, Elif; Feig, Daniel; Freundlich, Michael; Gaut, Joseph; Gbadegesin, Rasheed; Hanna, Melisha; Hidalgo, Guillermo; Hooper, David; Hunley, Tracy E.; Jain, Amrish; Kallash, Mahmoud; Kamel, Margo; Khalid, Myda; Klein, Jon B.; Kump, Theresa; Lane, Jerome C.; Liapis, Helen; Mahan, John; Mathews, Nisha; Nester, Carla; Pan, Cynthia; Patterson, Larry; Patel, Hiren; Raad, Alice; Revell, Adelaide; Rheault, Michelle N.; Silva, Cynthia; Sreedharan, Rajasree; Srivastava, Tarak; Steinke, Julia; Sumner, Susan; Twombley, Katherine; Wenderfer, Scott E.; Vasylyeva, Tetyana L.; Wang, Chia-shi; Weaver, Donald J.; Wong, Craig S.; Yin, Hong; Achanti, Anand; Almaani, Salem; Ayoub, Isabelle; Budisavljevic, Milos; D'Angelo, Maggie; Derebail, Vimal; Fatima, Huma; Falk, Ronald; Fogo, Agnes; Gibson, Keisha; Glenn, Dorey; Hogan, Susan; Jain, Koyal; Jennette, J. Charles; Julian, Bruce; Kidd, Jason; Laurin, Louis-Philippe; Massey, H. Davis; Mottl, Amy; Murphy, Shannon; Nadasdy, Tibor; Novak, Jan; Parikh, Samir; Poulton, Caroline; Powell, Thomas Brian; Reeve, Bryce; Renfrow, Matthew; Reynolds, Monica; Rizk, Dana; Rovin, Brad; Royal, Virginie; Saha, Manish; Sanghani, Neil; Self, Sally; Adler, Sharon; Alachkar, Nada; Alpers, Charles; Matar, Raed Bou; Avila-Casado, Carmen; Bagnasco, Serena; Brede, Emily; Brown, Elizabeth; Cattran, Daniel; Choi, Michael; Contreras, Gabriel; Dell, Katherine M.; Dewalt, Darren; Denburg, Michelle; Dukkipati, Ram; Fervenza, Fernando C.; Fornoni, Alessia; Gadegbeku, Crystal; Gipson, Patrick; Gonzalez-Zea, Anny; Hasely, Leah; Hendren, Elizabeth; Hingorani, Sangeeta; Hladunewich, Michelle; Hogan, Jonathan; Holzman, Lawrence B.; Hou, Jean; Jefferson, J. Ashley; Jhaveri, Kenar; Johnstone, Duncan B.; Kaskel, Frederick; Kogan, Amy; Kopp, Jeffrey; Lafayette, Richard; Lemley, Kevin V.; Malaga-Dieguez, Laura; Meyers, Kevin; Neu, Alicia; O'Shaughnessy, Michelle Marie; O’Toole, John F.; Oliverio, Andrea; Palmer, Matthew; Parekh, Rulan; Pitter, Renee; Reich, Heather; Reidy, Kimberly; Rondon, Helbert; Sambandam, Kamalanathan K.; Sampson, Matthew; Sedor, John R.; Selewski, David T.; Sethna, Christine B.; Schelling, Jeffrey; Sperati, John C.; Swiatecka-Urban, Agnes; Trachtman, Howard; Tuttle, Katherine R.; Waldman, Meryl; Weisstuch, Joseph; Wiggins, Roger; Williams, David; Winkler, Cheryl; Vento, Suzanne; Young, Eric; Zhdanova, Olga; Barisoni, Laura; Beil, Charlotte; Eikstadt, Richard; Gillespie, Brenda; Gipson, Debbie S.; Graff, John; Hewitt, Stephen; Hill-Callahan, Peg; Helmuth, Margaret; Herreshoff, Emily; Kretzler, Matthias; Lienczewski, Chrysta; Mansfield, Sarah; Mariani, Laura; McCullough, Keith; Moore, Nicholas; Nast, Cynthia C.; Robinson, Bruce M.; Sexton, Melissa; Troost, Jonathan; Wladkowski, Matthew; Zee, Jarcy; Zinsser, Dawn; Guay-Woodford, Lisa M.
Source
American Journal of Kidney Diseases; February 2019, Vol. 73 Issue: 2 p218-229, 12p
Subject
Language
ISSN
02726386; 15236838
Abstract
Glomerular diseases, including minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, and immunoglobulin A (IgA) nephropathy, share clinical presentations, yet result from multiple biological mechanisms. Challenges to identifying underlying mechanisms, biomarkers, and new therapies include the rarity of each diagnosis and slow progression, often requiring decades to measure the effectiveness of interventions to prevent end-stage kidney disease (ESKD) or death.