학술논문
The association between the −374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status the Hoorn and CoDAM studies
Document Type
Article
Author
Source
Journal of Hypertension; February 2010, Vol. 28 Issue: 2 p285-293, 9p
Subject
Language
ISSN
02636352; 14735598
Abstract
Receptor for advanced glycation endproducts (RAGE)–ligand interaction may lead to vascular complications. Genetic variation in RAGE has been shown to alter expression, activity of RAGE or both. We, therefore, investigated whether RAGE single-nucleotide polymorphisms (SNPs) and haplotypes were associated with vascular disease.