부산대학교 도서관

Circulating microRNAs (ci-miRs) are post-transcriptional regulators of gene expression released by cells into blood or other biofluids. Acute and chronic exercise have been shown to alter the profile of ci-miRs. The past few years have seen an upsurge in research detailing the exercise responses of ci-miRs and investigating their utility as biomarkers for various conditions. The functions of ci-miRs as paracrine/endocrine mediators of systemic adaptations to exercise training are also strongly suggested, but direct evidence is still lacking. The purpose of this review is to provide an update on recent advancements concerning ci-miRs in the field of exercise physiology.