학술논문
Tobacco Exposure and Efficacy of Biologic Therapy in Patients With Severe Asthma: A Nationwide Study From the Danish Severe Asthma Register
Document Type
Article
Author
Baastrup Soendergaard, Marianne; Hansen, Susanne; Bjerrum, Anne-Sofie; von Bülow, Anna; Haakansson, Kjell Erik Julius; Hilberg, Ole; Ingebrigtsen, Truls Sylvan; Johnsen, Claus Rikard; Lock-Johansson, Sofie; Makowska Rasmussen, Linda; Schmid, Johannes Martin; Ulrik, Charlotte Suppli; Porsbjerg, Celeste
Source
The Journal of Allergy and Clinical Immunology: In Practice; 20230101, Issue: Preprints
Subject
Language
ISSN
22132198
Abstract
Randomized trials of biologics in severe, uncontrolled asthma have excluded patients with a cumulative tobacco exposure of more than 10 pack-years. Therefore, our knowledge of the impact of smoking exposure on the clinical effects of biologics in severe asthma remains incomplete. However, because many patients with asthma are current or former smokers, investigating the potential impacts of tobacco exposure on the effects of biologic treatment is clinically important.