학술논문
Implications of the non-specific effect induced by Bacillus Calmette-Guerin(BCG) vaccine on vaccine recommendations
Document Type
Article
Source
Jornal de Pediatria; March-April 2023, Vol. 99 Issue: 1, Number 1 Supplement 1 pS22-S27, 6p
Subject
Language
ISSN
00217557; 16784782
Abstract
Since the beginning of its use for the prevention of tuberculosis (TB) in 1921, other uses of BCG (Bacillus Calmette-Guérin) have been proposed, particularly in the treatment of malignant solid tumors, multiple sclerosis, and other autoimmune diseases. Its beneficial impact on other infections, by nontuberculous mycobacteria, and by viruses, has been more often studied in recent years, especially after the introduction of the concept of trained immunity. The present study's objective was to review the possible indications of BCG and the immunological rationale for these indications.