학술논문

Structure and mobilization of an ampicillin and gentamicin resistance determinant
Document Type
Article
Source
Antimicrobial Agents and Chemotherapy; August 1987, Vol. 31 Issue: 8 p1266-1270, 5p
Subject
Language
ISSN
00664804; 10986596
Abstract
A DNA segment originally found in an epidemic plasmid of Escherichia coli encoding an aminoglycoside-(3)-N-acetyltransferase gene (aacC5) and a TEM-type beta-lactamase gene was characterized. The two genes were adjacent and constituted a single transcriptional unit. In addition, these genes were simultaneously mobilized through the action of an insertion sequence related to IS26, IS140, and IS15-delta. This DNA segment is a composite transposon which has been called Tn2922.