학술논문
Complete attenuation of genetically engineered Plasmodium falciparumsporozoites in human subjects
Document Type
Article
Author
Kublin, James G.; Mikolajczak, Sebastian A.; Sack, Brandon K.; Fishbaugher, Matt E.; Seilie, Annette; Shelton, Lisa; VonGoedert, Tracie; Firat, Melike; Magee, Sara; Fritzen, Emma; Betz, Will; Kain, Heather S.; Dankwa, Dorender A.; Steel, Ryan W. J.; Vaughan, Ashley M.; Noah Sather, D.; Murphy, Sean C.; Kappe, Stefan H. I.
Source
Science Translational Medicine; January 2017, Vol. 9 Issue: 371
Subject
Language
ISSN
19466234; 19466242
Abstract
A genetically attenuated Plasmodium falciparumstrain called Pf GAP3KO is completely attenuated, safe, and immunogenic in adults.