학술논문
Tumor microenvironment of Burkitt lymphoma: different immune signatures with different clinical behavior
Document Type
Article
Author
Siciliano, Maria Chiara; Bertolazzi, Giorgio; Morello, Gaia; Tornambè, Salvatore; Del Corvo, Marcello; Granai, Massimo; Sapienza, Maria Rosaria; Leahy, Ciara I.; Fennell, Eanna; Belmonte, Beatrice; Arcuri, Felice; Vannucchi, Margherita; Mancini, Virginia; Guazzo, Raffaella; Boccacci, Roberto; Onyango, Noel; Nyagol, Joshua; Santi, Raffaella; Di Stefano, Gioia; Ferrara, Domenico; Bellan, Cristiana; Marafioti, Teresa; Ott, German; Siebert, Reiner; Quintanilla-Fend, Leticia; Fend, Falko; Murray, Paul; Tripodo, Claudio; Pileri, Stefano; Lazzi, Stefano; Leoncini, Lorenzo
Source
Blood Advances; 20240101, Issue: Preprints
Subject
Language
ISSN
24739529; 24739537
Abstract
•BL with granulomatous reaction was characterized by an M1 signature and INFG in CD8+ cells, whereas BL with starry sky showed M2 genes.•Tumor-associated macrophages repolarization and epigenetic regulators may open new therapeutic options for the fight against BL lymphoma.