학술논문

Plant protein substitution for animal protein and its association with cardiovascular risk factors and inflammatory biomarkers in elderly men: A substitution analysis
Document Type
Article
Source
Nutrition and Healthy Aging; May 2024, Vol. 9 Issue: 1 p91-99, 9p
Subject
Language
ISSN
24519480; 24519502
Abstract
Substituting different types of protein intake may be associated with cardiovascular risk factors and inflammatory biomarkers. However, there are few studies conducted on elders and the findings are contradictory. We decided to examine the association of substituting plant protein for animal protein with cardiovascular risk factors and inflammatory biomarkers among elderly men. The current cross-sectional study included 357 elderly men chosen from health centres in southern Tehran, Iran. They provide written consent to be included in the study. We used a validated and reliable food frequency questionnaire (FFQ) to assess dietary intake. All biochemical factors like lipid profile, fasting blood sugar (FBS), high sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL6), tumor necrosis factor-α (TNF-α) were measured. Waist circumference (WC) and blood pressure (BP) were also assessed. The substitution analysis by STATA was used to examine the aforementioned association. Substituting animal protein with plant protein had significant beneficial association with WC (OR: –4.28; 95% CI: –8.51, –0.62; Ptrend = 0.047) and LDL/HDL (OR: –0.26; 95% CI: –0.48, –0.05; Ptrend = 0.018). In elderly men, substituting animal protein with plant protein had favorable association with some of cardiovascular risk factors including WC and LDL/HDL but there was no significant association for inflammatory biomarkers.