학술논문

Anti-asialo-GM1 and GD1a Variant of Miller Fisher Variant of Guillain–Barré Syndrome
Document Type
Article
Source
Journal of Neuro-Ophthalmology; December 2014, Vol. 34 Issue: 4 p377-379, 3p
Subject
Language
ISSN
10708022; 15365166
Abstract
We present a woman with acute onset of bilateral ophthalmoparesis and ataxia occurring 4 weeks after gastroenteritis. Serum antibody titers against asialo-GM1 and GD1a, typically associated with inflammatory axonal neuropathies, were elevated but titers against anti-GQ1b, the most commonly found antibody found in the Miller Fisher variant of Guillain–Barre syndrome were not. No other etiology for ophthalmoparesis was found despite extensive patient evaluation. Intravenous immunoglobulin was administered, and the patient gradually improved over subsequent months. This case is unique for its antiganglioside antibody profile associated with Miller Fisher syndrome.