학술논문
Club 35 Poster session Friday 13 December: 13/12/2013, 08:30-18:00 * Location: Poster area
Document Type
Article
Author
Ben Abda, A; Hachulla, E; Polge, AS; Richardson, M; Duva Penthia, A; De Groote, P; Montaigne, D; Lamblin, N; Lamer, M; Cinotti, R; Delater, A; Asehnoune, K; Blanloeil, Y; Le Tourneau, T; Rozec, B; Piriou, N; Moon, J; Kim, TH; Ahn, T; Chung, WJ; Chimura, M; Oonishi, T; Tukishiro, Y; Yamada, S; Taniguchi, Y; Yasaka, Y; Kawai, T; Elmissiri, AM; Andres Lahuerta, A; Alonso Fernandez, P; Igual Munoz, B; Osca Asensi, J; Cano Perez, O; Jimenez Carreno, R; Sancho-Tello De Carranza, MJ; Olague De Ros, J; Salvador Sanz, A; Atas, H; Samadov, F; Kepez, A; Sunbul, M; Cincin, A; Direskeneli, H; Tigen, K; Yildiz, A; Karakas, MF; Cimen, T; Tuncez, A; Korkmaz, A; Uygur, B; Isleyen, A; Tufekcioglu, O; Melao, F; Paiva, M; Goncalves, A; Pinho, T; Madureira, A; Martins, E; Macedo, F; Maciel, MJ; Guvenc, TS; Erer, HB; Kul, S; Oz, D; Koroglu, B; Kaya, Y; Koc, S; Sayar, N; Degirmencioglu, A; Eren, M; Stapor, M; Condemi, F; Bapat, V; Gianstefani, S; Catibog, N; Monaghan, M J; Carro, A; Pijuan, A; Dos, L; Huguet, F; Abad, C; Gonzalez, N; Miranda, B; Galian, L; Casaldaliga, J; Evangelista, A; Gurzun, M M; Ionescu, A; Kahraman, E; Sen, T; Guven, S; Keskin, G; Topaloglu, S; Korkmaz, S; Moatemri, F; Mahdhaoui, A; Bouraoui, H; Jeridi, G; Ernez, S; Basaran, O; Gozubuyuk, G; Dundar, C; Tasar, O; Bulut, M; Karaahmet, T; Pala, S; Tigen, K; Izgi, A; Kirma, C; Baronaite-Dudoniene, K; Urbaite, L; Smalinskas, V; Veisaite, R; Vasylius, T; Vaskelyte, J; Puodziukynas, A; Carro, A; Teixido-Tura, G; Rodriguez-Palomares, JF; Cuellar, H; Pineda, V; Gruosso, D; Gutierrez, L; Moral, S; Gonzalez-Alujas, MT; Evangelista, A; Oprescu, N; Micheu, M; Calmac, L; Pitic, D; Dorobantu, M; Brugger, N; Huerzeler, M; Wustmann, K; Wahl, A; Steck, H; Seiler, C; Ismail, H; Linde, JJ; Kofoed, KF; Dixen, U; Soergaard, M; Hove, JD; Willis, J; Oxborough, D; Augustine, DX; Knight, D; Coghlan, G; Shah, R; Easaw, J; Verseckaite, R; Pilkauskaite, G; Lapinskas, T; Miliauskas, S; Sakalauskas, R; Jurkevicius, R; Ozeke, O; Turak, O; Ozcan, F; Cay, S; Topaloglu, S; Aras, D; Tufekcioglu, O; Golbasi, Z; Aydogdu, S
Source
European Journal of Echocardiography; December 2013, Vol. 14 Issue: Supplement 2 pii135-ii135, 1p
Subject
Language
ISSN
15252167; 15322114
Abstract
Background: Systemic sclerosis (SSc) is a rare connective tissue disease that can lead to severe heart complications, i.e. congestive heart failure, arrhythmia and sudden cardiac death. The latter are associated with poor prognosis in SSc. The aim of this study was to test whether infra-clinical myocardial dysfunction can be detected in patients with SSc free from cardiovascular symptoms. Methods: Global LV, and segmental right ventricular longitudinal strain (2D-speckle tracking strain) were quantified by transthoracic echocardiography to assess ventricular deformations in 48 patients suffering from SSc and 40 matched control subjects. Results: Despite normal LVEF, patients presenting SSc had significantly impaired LV GLS in compared to controls (17.9 +/- 3.04 % vs -19.4+/- 2.3 %; p= 0.01). By contrast, there was no significant difference on lateral and inferior RV strain between patients and controls. Decreased LV deformation was detected in patients regardless of pulmonary injury, i.e. restrictive syndrome and pulmonary arterial hypertension (PAH). Patients with diffuse cutaneous SSc had impaired (GLV?) LV and RV strains in 4 and 2 chamber views compared to those presenting a limited form of cutaneous SSc, with respectively, -18.9 +/- 3.47% vs -16.6+/- 3.70%, p=0.039 and -19.7+/- 2.93% versus -17.6+/- 3.40% p=0.047. Conclusion: Speckle-tracking strain analysis can detect infra-clinical impairment of LV myocardial function in patients with SSc who are free from any cardiovascular symptoms regardless of SSc impact on pulmonary function. Right and Left ventricular strain in Ssc