학술논문
Poster session Friday 13 December - PM: 13/12/2013, 14:00-18:00 * Location: Poster area
Document Type
Article
Author
Caiani, EG; Pellegrini, A; Carminati, MC; Lang, RM; Auricchio, A; Vaida, P; Obase, K; Sakakura, T; Komeda, M; Okura, H; Yoshida, K; Zeppellini, R; Noni, M; Rigo, T; Erente, G; Carasi, M; Costa, A; Ramondo, BA; Thorell, L; Akesson-Lindow, T; Shahgaldi, K; Germanakis, I; Fotaki, A; Peppes, S; Sifakis, S; Parthenakis, F; Makrigiannakis, A; Richter, U; Sveric, K; Forkmann, M; Wunderlich, C; Strasser, RH; Djikic, D; Potpara, T; Polovina, M; Marcetic, Z; Peric, V; Ostenfeld, E; Werther-Evaldsson, A; Engblom, H; Ingvarsson, A; Roijer, A; Meurling, C; Holm, J; Radegran, G; Carlsson, M; Tabuchi, H; Yamanaka, T; Katahira, Y; Tanaka, M; Kurokawa, T; Nakajima, H; Ohtsuki, S; Saijo, Y; Yambe, T; Dalto, M; Romeo, E; Argiento, P; Dandrea, A; Vanderpool, R; Correra, A; Sarubbi, B; Calabro, R; Russo, MG; Naeije, R; Saha, S K; Warsame, T A; Caelian, A G; Malicse, M; Kiotsekoglou, A; Omran, A S; Sharif, D; Sharif-Rasslan, A; Shahla, C; Khalil, A; Rosenschein, U; Erturk, M; Oner, E; Kalkan, AK; Pusuroglu, H; Ozyilmaz, S; Akgul, O; Aksu, HU; Akturk, F; Celik, O; Uslu, N; Bandera, F; Pellegrino, M; Generati, G; Donghi, V; Alfonzetti, E; Guazzi, M; Rangel, I; Goncalves, A; Sousa, C; Correia, AS; Martins, E; Silva-Cardoso, J; Macedo, F; Maciel, MJ; Lee, S; Kim, W; Yun, H; Jung, L; Kim, E; Ko, J; Enescu, OA; Florescu, M; Rimbas, RC; Cinteza, M; Vinereanu, D; Kosmala, W; Rojek, A; Cielecka-Prynda, M; Laczmanski, L; Mysiak, A; Przewlocka-Kosmala, M; Liu, D; Hu, K; Niemann, M; Herrmann, S; Cikes, M; Gaudron, PD; Knop, S; Ertl, G; Bijnens, B; Weidemann, F; Saravi, M; Tamadoni, AHMAD; Jalalian, ROZITA; Hojati, MOSTAF; Ramezani, SAEED; Yildiz, A; Inci, U; Bilik, MZ; Yuksel, M; Oyumlu, M; Kayan, F; Ozaydogdu, N; Aydin, M; Akil, MA; Tekbas, E; Shang, Q; Zhang, Q; Fang, F; Wang, S; Li, R; Lee, A PW; Yu, CM; Mornos, C; Ionac, A; Cozma, D; Popescu, I; Ionescu, G; Dan, R; Petrescu, L; Sawant, AC; Srivatsa, SV; Adhikari, P; Mills, PK; Srivatsa, SS; Boshchenko, A; Vrublevsky, A; Karpov, R; Trifunovic, D; Stankovic, S; Vujisic-Tesic, B; Petrovic, M; Nedeljkovic, I; Banovic, M; Tesic, M; Petrovic, M; Dragovic, M; Ostojic, M; Zencirci, E; Esen Zencirci, A; Degirmencioglu, A; Karakus, G; Ekmekci, A; Erdem, A; Ozden, K; Erer, HB; Akyol, A; Eren, M; Zamfir, D; Tautu, O; Onciul, S; Marinescu, C; Onut, R; Comanescu, I; Oprescu, N; Iancovici, S; Dorobantu, M; Melao, F; Pereira, M; Ribeiro, V; Oliveira, S; Araujo, C; Subirana, I; Marrugat, J; Dias, P; Azevedo, A; study, EURHOBOP; Grillo, M T; Piamonti, B; Abate, E; Porto, A; Dellangela, L; Gatti, G; Poletti, A; Pappalardo, A; Sinagra, G; Pinto-Teixeira, P; Galrinho, A; Branco, L; Fiarresga, A; Sousa, L; Cacela, D; Portugal, G; Rio, P; Abreu, J; Ferreira, R; Fadel, B; Abdullah, N; Al-Admawi, M; Pergola, V; Bech-Hanssen, O; Di Salvo, G; Tigen, M K; Pala, S; Karaahmet, T; Dundar, C; Bulut, M; Izgi, A; Esen, A M; Kirma, C; Boerlage-Van Dijk, K; Yamawaki, M; Wiegerinck, EMA; Meregalli, PG; Bindraban, NR; Vis, MM; Koch, KT; Piek, JJ; Bouma, BJ; Baan, J; Mizia, M; Sikora-Puz, A; Gieszczyk-Strozik, K; Lasota, B; Chmiel, A; Chudek, J; Jasinski, M; Deja, M; Mizia-Stec, K; Silva Fazendas Adame, P R; Caldeira, D; Stuart, B; Almeida, S; Cruz, I; Ferreira, A; Lopes, L; Joao, I; Cotrim, C; Pereira, H; Unger, P; Dedobbeleer, C; Stoupel, E; Preumont, N; Argacha, JF; Berkenboom, G; Van Camp, G; Malev, E; Reeva, S; Vasina, L; Pshepiy, A; Korshunova, A; Timofeev, E; Zemtsovsky, E; Jorgensen, P G; Jensen, JS; Fritz-Hansen, T; Biering-Sorensen, T; Jons, C; Olsen, NT; Henri, C; Magne, J; Dulgheru, R; Laaraibi, S; Voilliot, D; Kou, S; Pierard, L; Lancellotti, P; Tayyareci, Y; Dworakowski, R; Kogoj, P; Reiken, J; Kenny, C; Maccarthy, P; Wendler, O; Monaghan, MJ; Song, JM; Ha, TY; Jung, YJ; Seo, MO; Choi, SA; Kim, YJ; Sun, BJ; Kim, DH; Kang, DH; Song, JK; Le Tourneau, T; Topilsky, Y; Inamo, J; Mahoney, D; Suri, R; Schaff, H; Enriquez-Sarano, M; Bonaque Gonzalez, JC; Sanchez Espino, AD; Merchan Ortega, G; Bolivar Herrera, N; Ikuta, I; Macancela Quinonez, JJ; Munoz Troyano, S; Ferrer Lopez, R; Gomez Recio, M; Dreyfus, J; Cimadevilla, C; Brochet, E; Himbert, D; Iung, B; Vahanian, A; Messika-Zeitoun, D; Izumo, M; Takeuchi, M; Seo, Y; Yamashita, E; Suzuki, K; Ishizu, T; Sato, K; Aonuma, K; Otsuji, Y; Akashi, YJ; Muraru, D; Addetia, K; Veronesi, F; Corsi, C; Mor-Avi, V; Yamat, M; Weinert, L; Lang, RM; Badano, LP; Minamisawa, M; Koyama, J; Kozuka, A; Motoki, H; Izawa, A; Tomita, T; Miyashita, Y; Ikeda, U; Florescu, C; Niemann, M; Liu, D; Hu, K; Herrmann, S; Gaudron, PD; Scholz, F; Stoerk, S; Ertl, G; Weidemann, F; Marchel, M; Serafin, A; Kochanowski, J; Piatkowski, R; Madej-Pilarczyk, A; Filipiak, KJ; Hausmanowa-Petrusewicz, I; Opolski, G; Meimoun, P; Mbarek, D; Clerc, J; Neikova, A; Elmkies, F; Tzvetkov, B; Luycx-Bore, A; Cardoso, C; Zemir, H; Mansencal, N; Arslan, M; El Mahmoud, R; Pilliere, R; Dubourg, O; Ikonomidis, I; Lambadiari, V; Pavlidis, G; Koukoulis, C; Kousathana, F; Varoudi, M; Tritakis, V; Triantafyllidi, H; Dimitriadis, G; Lekakis, I; Kovacs, A; Kosztin, A; Solymossy, K; Celeng, C; Apor, A; Faludi, M; Berta, K; Szeplaki, G; Foldes, G; Merkely, B; Kimura, K; Daimon, M; Nakajima, T; Motoyoshi, Y; Komori, T; Nakao, T; Kawata, T; Uno, K; Takenaka, K; Komuro, I; Gabric, I D; Vazdar, LJ; Pintaric, H; Planinc, D; Vinter, O; Trbusic, M; Bulj, N; Nobre Menezes, M; Silva Marques, J; Magalhaes, R; Carvalho, V; Costa, P; Brito, D; Almeida, AG; Nunes-Diogo, AG; Davidsen, E S; Bergerot, C; Ernande, L; Barthelet, M; Thivolet, S; Decker-Bellaton, A; Altman, M; Thibault, H; Moulin, P; Derumeaux, G; Huttin, O; Voilliot, D; Frikha, Z; Aliot, E; Venner, C; Juilliere, Y; Selton-Suty, C; Yamada, T; Ooshima, M; Hayashi, H; Okabe, S; Johno, H; Murata, H; Charalampopoulos, A; Tzoulaki, I; Howard, LS; Davies, RJ; Gin-Sing, W; Grapsa, J; Wilkins, MR; Gibbs, JSR; Castillo, JMDC; Bandeira, AMPB; Albuquerque, ESA; Silveira, C; Pyankov, V; Chuyasova, Y; Lichodziejewska, B; Goliszek, S; Kurnicka, K; Dzikowska Diduch, O; Kostrubiec, M; Krupa, M; Grudzka, K; Ciurzynski, M; Palczewski, P; Pruszczyk, P; Arana, X; Oria, G; Onaindia, JJ; Rodriguez, I; Velasco, S; Cacicedo, A; Palomar, S; Subinas, A; Zumalde, J; Laraudogoitia, E; Saeed, S; Kokorina, MV; Fromm, A; Oeygarden, H; Waje-Andreassen, U; Gerdts, E; Gomez, ELENA; Vallejo, NURIA; Pedro-Botet, LUISA; Mateu, LOURDE; Nunyez, RAQUEL; Llobera, LAIA; Bayes, ANTONI; Sabria, MIQUEL; Antonini-Canterin, F; Mateescu, AD; La Carrubba, S; Vriz, O; Di Bello, V; Carerj, S; Zito, C; Ginghina, C; Popescu, BA; Nicolosi, GL; Mateescu, AD; La Carrubba, S; Vriz, O; Di Bello, V; Carerj, S; Zito, C; Ginghina, C; Popescu, BA; Nicolosi, GL; Antonini-Canterin, F; Pudil, R; Praus, R; Vasatova, M; Vojacek, J; Palicka, V; Hulek, P; P37/03, Prvouk; Pradel, S; Mohty, D; Damy, T; Echahidi, N; Lavergne, D; Virot, P; Aboyans, V; Jaccard, A; Mateescu, AD; La Carrubba, S; Vriz, O; Di Bello, V; Carerj, S; Zito, C; Ginghina, C; Popescu, BA; Nicolosi, GL; Antonini-Canterin, F; Doulaptsis, C; Symons, R; Matos, A; Florian, A; Masci, PG; Dymarkowski, S; Janssens, S; Bogaert, J; Lestuzzi, C; Moreo, A; Celik, S; Lafaras, C; Dequanter, D; Tomkowski, W; De Biasio, M; Cervesato, E; Massa, L; Imazio, M; Watanabe, N; Kijima, Y; Akagi, T; Toh, N; Oe, H; Nakagawa, K; Tanabe, Y; Ikeda, M; Okada, K; Ito, H; Milanesi, O; Biffanti, R; Varotto, E; Cerutti, A; Reffo, E; Castaldi, B; Maschietto, N; Vida, VL; Padalino, M; Stellin, G; Bejiqi, R; Retkoceri, R; Bejiqi, H; Retkoceri, A; Surdulli, SH; Massoure, PL; Cautela, J; Roche, NC; Chenilleau, MC; Gil, JM; Fourcade, L; Akhundova, A; Cincin, A; Sunbul, M; Sari, I; Tigen, MK; Basaran, Y; Suermeci, G; Butz, T; Schilling, IC; Sasko, B; Liebeton, J; Van Bracht, M; Tzikas, S; Prull, MW; Wennemann, R; Trappe, HJ; Attenhofer Jost, C H; Pfyffer, M; Scharf, C; Seifert, B; Faeh-Gunz, A; Naegeli, B; Candinas, R; Medeiros-Domingo, A; Wierzbowska-Drabik, K; Roszczyk, N; Sobczak, M; Plewka, M; Krecki, R; Kasprzak, JD; Ikonomidis, I; Varoudi, M; Papadavid, E; Theodoropoulos, K; Papadakis, I; Pavlidis, G; Triantafyllidi, H; Anastasiou - Nana, M; Rigopoulos, D; Lekakis, J; Tereshina, O; Surkova, E; Vachev, A; Merchan Ortega, G; Bonaque Gonzalez, JC; Sanchez Espino, AD; Bolivar Herrera, N; Bravo Bustos, D; Ikuta, I; Aguado Martin, MJ; Navarro Garcia, F; Ruiz Lopez, F; Gomez Recio, M; Merchan Ortega, G; Bonaque Gonzalez, JC; Bravo Bustos, D; Sanchez Espino, AD; Bolivar Herrera, N; Bonaque Gonzalez, JJ; Navarro Garcia, F; Aguado Martin, MJ; Ruiz Lopez, MF; Gomez Recio, M; Eguchi, H; Maruo, T; Endo, K; Nakamura, K; Yokota, K; Fuku, Y; Yamamoto, H; Komiya, T; Kadota, K; Mitsudo, K; Nagy, A I; Manouras, AI; Gunyeli, E; Shahgaldi, K; Winter, R; Hoffmann, R; Barletta, G; Von Bardeleben, S; Kasprzak, J; Greis, C; Vanoverschelde, J; Becher, H; Hu, K; Liu, D; Niemann, M; Herrmann, S; Cikes, M; Gaudron, PD; Knop, S; Ertl, G; Bijnens, B; Weidemann, F; Di Salvo, G; Al Bulbul, Z; Issa, Z; Khan, AM; Faiz, AA; Rahmatullah, SH; Fadel, BM; Siblini, G; Al Fayyadh, M; Menting, M E; Van Den Bosch, AE; Mcghie, JS; Cuypers, JAAE; Witsenburg, M; Van Dalen, BM; Geleijnse, ML; Roos-Hesselink, JW; Olsen, FJ; Jorgensen, PG; Mogelvang, R; Jensen, JS; Fritz-Hansen, T; Bech, J; Biering-Sorensen, T; Agoston, G; Pap, R; Saghy, L; Forster, T; Varga, A; Scandura, S; Capodanno, D; Dipasqua, F; Mangiafico, S; Caggegi, A M; Grasso, C; Pistritto, A M; Imme, S; Ministeri, M; Tamburino, C; Cameli, M; Lisi, M; Dascenzi, F; Cameli, P; Losito, M; Sparla, S; Lunghetti, S; Favilli, R; Fineschi, M; Mondillo, S; Ojaghihaghighi, Z; Javani, B; Haghjoo, M; Moladoust, H; Shahrzad, S; Ghadrdoust, B; Altman, M; Aussoleil, A; Bergerot, C; Bonnefoy-Cudraz, E; Derumeaux, G A; Thibault, H; Shkolnik, E; Vasyuk, Y; Nesvetov, V; Shkolnik, L; Varlan, G; Gronkova, N; Kinova, E; Borizanova, A; Goudev, A; Saracoglu, E; Ural, D; Sahin, T; Al, N; Cakmak, H; Akbulut, T; Akay, K; Ural, E; Mushtaq, S; Andreini, D; Pontone, G; Bertella, E; Conte, E; Baggiano, A; Annoni, A; Formenti, A; Fiorentini, C; Pepi, M; Cosgrove, C; Carr, L; Chao, C; Dahiya, A; Prasad, S; Younger, JF; Biering-Sorensen, T; Christensen, LM; Krieger, DW; Mogelvang, R; Jensen, JS; Hojberg, S; Host, N; Karlsen, FM; Christensen, H; Medressova, A; Abikeyeva, L; Dzhetybayeva, S; Andossova, S; Kuatbayev, Y; Bekbossynova, M; Bekbossynov, S; Pya, Y; Farsalinos, K; Tsiapras, D; Kyrzopoulos, S; Spyrou, A; Stefopoulos, C; Romagna, G; Tsimopoulou, K; Tsakalou, M; Voudris, V; Cacicedo, A; Velasco Del Castillo, S; Anton Ladislao, A; Aguirre Larracoechea, U; Onaindia Gandarias, J; Romero Pereiro, A; Arana Achaga, X; Zugazabeitia Irazabal, G; Laraudogoitia Zaldumbide, E; Lekuona Goya, I; Varela, A; Kotsovilis, S; Salagianni, M; Andreakos, V; Davos, CH; Merchan Ortega, G; Bonaque Gonzalez, JC; Sanchez Espino, AD; Bolivar Herrera, N; Macancela Quinones, JJ; Ikuta, I; Ferrer Lopez, R; Munoz Troyano, S; Bravo Bustos, D; Gomez Recio, M
Source
European Journal of Echocardiography; December 2013, Vol. 14 Issue: Supplement 2 pii176-ii176, 1p
Subject
Language
ISSN
15252167; 15322114
Abstract
Purpose: Cardiac deconditioning due to immobilization is a risk factor for cardiovascular disease. The physiology of cardiac adaptation to deconditioning has not been fully elucidated. The purpose of the present study was to assess the effects of 21-days of strict head-down (-6 degrees) bed-rest (BR) deconditioning on left ventricular (LV) dimensions and mass measured by MRI. Methods: Ten healthy men (mean age 32±6) were enrolled; the experiment was conducted at DLR (Koln, Germany) as part of the European Space Agency BR studies. Steady-state free precession MRI images (7mm thickness, no gap, no overlap) were obtained (Symphony 1.5T, Siemens) in a stack of short-axis views from LV base to LV apex, before (PRE), at the end of BR (HDT20), and four days after the BR conclusion (POST). Endocardial and epicardial semi-automated contouring was performed using freely available software (Segment). Results: At HDT20, significant reductions in LV mass (16%), end-diastolic (26%) and end-systolic (27%) volumes and stroke volume (27%) were observed, while ejection fraction did not change. These changes were accompanied by a measured decrease (14%) in plasma and blood volume (by gas-rebreathing technique), as well as by a significant reduction (14%) in VO2max aerobic power, measured using a graded cycle ergometer test protocol to volitional fatigue, at one day after the BR conclusion, while expiratory exchange ratio did not change. At POST, LV volumes were restored, while LV mass was still trending towards control values. Conclusions: Cardiac adaptation to deconditioning affected LV mass and dimensions, as a combined result of LV remodeling and fluids loss, accompanied by worsening in aerobic power. This should be taken into account in patients with cardiovascular diseases, when immobilized in bed, to proper adjust the therapy, or to define appropriate physical exercises when possible, in order to avoid further complications. Cardiac MRI parameters PRE HDT20 POST LV mass (g) 121±6 102±11* 114±16 End-diastolic volume (ml) 119±25 90±14* 118±25 End-systolic volume (ml) 42±8 31±8* 45±14 Stroke volume (ml) 76±22 59±11* 73±15 Ejection fraction (%) 64±6 65±7 62±7 *: p<.01 vs PRE (one-way Anova for paired data and Tukey test)