학술논문
Lung ventilation and perfusion scintigraphy in the follow up of repaired congenital diaphragmatic hernia
Document Type
Article
Source
European Journal of Nuclear Medicine and Molecular Imaging; September 1989, Vol. 15 Issue: 9 p591-596, 6p
Subject
Language
ISSN
16197070; 16197089
Abstract
To evaluate the effects of congenital diaphragmatic hernia (CDH) and pulmonary hypoplasia on subsequent lung function and development, we performed lung 133 Xe ventilation and 99m Tc perfusion scintigraphies in a group of infants who had undergone surgical repair of a severe left CDH with respiratory distress within the first 6 h of life. The initial lung scans performed in 15 children, 2–3 months of age, demonstrated a decreased ventilation in 7. In 9 children there was a trapping of 133 Xe at the left lung base. Perfusion to the hernia side was reduced in 8 of the children. We re-evaluated 11 of these 15 patients after 1–2 years. The ventilation to the left lung was still decreased in 3, but perfusion remained decreased in 9. After 5 years, ventilation to the hernia side was normal in 4 of the 5 patients studied, whereas pulmonary blood flow was abnormal in 4. These results show a progressive improvement of ventilation with a persisting reduction of perfusion to the lung of the hernia side, suggesting a primary vascular pulmonary hypoplasia in CDH.