학술논문
Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.
Document Type
Article
Author
Source
Proceedings of the National Academy of Sciences of the United States of America; May 1985, Vol. 82 Issue: 10 p3330-3334, 5p
Subject
Language
ISSN
00278424; 10916490
Abstract
The human type II collagen gene, COL2A1, has been assigned to chromosome 12, the type III gene, COL3A1, to chromosome 2, and one of the type IV genes, COL4A1, to chromosome 13. These assignments were made by using cloned genes as probes on Southern blots of DNA from a panel of mouse/human somatic cell hybrids. The two genes of type I collagen, COL1A1 and COL2A1, have been mapped previously to chromosomes 17 and 7, respectively. This family of conserved genes seems therefore to be dispersed throughout the genome.