학술논문
Smoking-induced immune deviation contributes to progression of bladder and other cancers
Document Type
Article
Source
OncoImmunology; September 2015, Vol. 4 Issue: 9
Subject
Language
ISSN
21624011; 2162402X
Abstract
We propose here that cigarette smoke (CS), in addition to its established genotoxic effects, elicits chronic albeit sub-clinical immune suppression, which is a major contributor to cancer progression. This hypothesis, presented here primarily in the context of bladder cancers (BCs), is applicable to other cancers, including those without a confirmed link to smoking.