학술논문
Octaphlorethol A Inhibits the CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase and NF-κB Pathways
Document Type
Article
Author
Source
Bioscience, Biotechnology, and Biochemistry; September 2013, Vol. 77 Issue: 9 p1970-1972, 3p
Subject
Language
ISSN
09168451; 13476947
Abstract
Octaphlorethol A is a phenolic compound isolated from the marine alga Ishige foliacea. In the present study, we investigated the anti-inflammatory activity of octaphlorethol A in CpG-stimulated primary murine bone marrow-derived macrophages and dendritic cells. It exhibited anti-inflammatory activity by regulating the mitogen-activated protein kinase and NF-κB pathways.