학술논문
Dry Mouth: An Overlooked Autonomic Symptom of Parkinson's Disease
Document Type
Article
Author
Source
Journal of Parkinson's Disease; January 2011, Vol. 1 Issue: 2 p169-173, 5p
Subject
Language
ISSN
18777171; 1877718x
Abstract
There is involvement of salivary glands by α-synuclein pathology in PD. However, the prevalence of dry mouth has not been systematically assessed in these patients. We studied 97 PD patients and 86 controls using a structured questionnaire. Dry mouth was reported by 60.8% of PD patients and 27.9% of controls (p < 0.0001). Dry mouth and drooling coexisted in 30% of cases. Only 12% of patients had reported dry mouth to their physicians. Dry mouth is a frequent but underreported symptom and may be an early manifestation of autonomic involvement in PD.