학술논문
Mainstream Smoke Chemistry and in Vitroand In VivoToxicity of the Reference Cigarettes 3R4F and 2R4F
Document Type
Article
Author
Source
Beiträge zur Tabakforschung International : Contributions to Tobacco Research; February 2012, Vol. 25 Issue: 1 p316-335, 20p
Subject
Language
ISSN
0173783X; 16129237
Abstract
A new reference cigarette, the 3R4F, has been developed to replace the depleting supply of the 2R4F cigarette. The present study was designed to compare mainstream smoke chemistry and toxicity of the two reference cigarettes under the International Organization for Standardization (ISO) machine smoking conditions, and to further compare mainstream smoke chemistry and toxicological activity of the 3R4F cigarette by two different smoking regimens, i.e., the machine smoking conditions specified by ISO and the Health Canada intensive (HCI) smoking conditions.