학술논문
Health economic analysis of polygenic risk score use in primary prevention of coronary artery disease – A system dynamics model
Document Type
Article
Author
Vernon, Stephen T.; Brentnall, Stuart; Currie, Danielle J; Peng, Cindy; Gray, Michael P.; Botta, Giordano; Mujwara, Deo; Nicholls, Stephen J.; Grieve, Stuart M.; Redfern, Julie; Chow, Clara; Levesque, Jean-Frederic; Meikle, Peter J.; Jennings, Garry; Ademi, Zanfina; Wilson, Andrew; Figtree, Gemma A.
Source
American Journal of Preventive Cardiology; June 2024, Vol. 18 Issue: 1
Subject
Language
ISSN
26666677
Abstract
Primary prevention programs utilising traditional risk scores fail to identify all individuals who suffer acute cardiovascular events. We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into the cardiovascular disease CVD primary prevention program in Australia, using a whole-of-system model.