부산대학교 도서관

Objective: The objective of the study was to compare the neonatal outcomes of large-for-gestational age (LGA) infants delivered by women with and without gestational diabetes mellitus (GDM).Methods: This was a retrospective study of LGA singleton infants of = 36 weeks of gestation born at the Gazi University Medical School Hospital between 2006-2009. Neonatal outcomes included hypoglycemia, polycythemia in early neonatal period and hospital admissions. The Chi-square and Student's t-test were used for comparing variables.Results: Seven hundred eligible infant- mother pairs were included into the study. 87 of them (12.4 %) were infants of diabetic mothers (IDMs) and 613 (87.6 %) were infants of non-IDMs. Incidence of hypoglycemia at the first hour were higher in diabetic group (12.8 %) compared to non-IDMs (5.3 %) (p=0.014). Polycythemia were also more frequently observed in IDMs (9.3 %) than non-IDMs (3.0 %) (p=0.010). Although overall hospital admission rates weren't different between groups, IDMs were more likely to be admitted due to resistant hypoglycemia (p=0.045).Conclusions: The results of this study suggested that LGA infants of women with GDM were at risk for hypoglycemia and polycythemia in early neonatal period. However, routine care was sufficient for healthy LGA infants from non-diabetic mothers.