학술논문
The mechanism of reaction of phosphoramidate monoanions with nucleophiles.
Document Type
Article
Author
Source
Australian Journal of Chemistry; 1976, Vol. 29 Issue: 5 p949-956, 8p
Subject
Language
ISSN
00049425; 14450038
Abstract
The kinetics of reaction of the N-(4-chlorophenyl)phosphoramidate monoanion in hydroxylamine buffer require an intermediate common to hydrolysis and hydroxylaminolysis. The intermediate is possibly an induced-dipole pair analogous to the ion pairs suggested for substitution at saturated carbon. The same type of intermediate may be a feature of the reactions of all phosphoramidate monoanions and of phosphate monoester monoanions and dianions.