학술논문
A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS
Document Type
Article
Author
Source
The Journal of Experimental Medicine; July 1939, Vol. 70 Issue: 1 p53-66, 14p
Subject
Language
ISSN
00221007; 15409538
Abstract
The virus of lymphocytic choriomeningitis can be sedimented in the ultracentrifuge and washed repeatedly; the virus retains its activity provided that a small amount of normal serum is present in the diluent. A soluble substance capable of fixing complement in the presence of immune serum can be separated from the virus. Washed virus fixes complement poorly. The serologically specific soluble antigen is widely distributed in tissues of infected guinea pigs, mice, and monkeys.