학술논문
Post Syrian war impact on susceptibility rates and trends in molecular characterization of Enterobacteriaceae
Document Type
Article
Author
Source
Future Microbiology; September 2018, Vol. 13 Issue: 12 p1419-1430, 12p
Subject
Language
ISSN
17460913; 17460921
Abstract
Objective:Describe susceptibility and molecular profiles among Enterobacteriaceaepathogens and to explore if war, among other factors, can affect antimicrobial resistance. Methods:Clinical isolates from the Study for Monitoring Antimicrobial Resistance Trends associated with urinary tract and intra-abdominal infections between 2011 and 2015 were identified in Lebanon and Jordan. Susceptibility testing and molecular characterization were performed as per standard methods. Results:A total of 1486 Enterobacteriaceaepathogens (including unusual pathogens) were identified. Incidence rates of extended spectrum β-lactamases were high with an overall higher prevalence of resistance in Jordan compared with Lebanon. CTX-M-15 was the most prevalent extended spectrum β-lactamases produced and OXA-48 the most reported carbapenemases subtype. Conclusion:Changes in healthcare system due to war could impact regional resistance patterns and which requires a continuous surveillance program and containment plan.