학술논문
Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey
Document Type
Article
Author
Tanriover, Mine Durusu; Doğanay, Hamdi Levent; Akova, Murat; Güner, Hatice Rahmet; Azap, Alpay; Akhan, Sıla; Köse, Şükran; Erdinç, Fatma Şebnem; Akalın, Emin Halis; Tabak, Ömer Fehmi; Pullukçu, Hüsnü; Batum, Özgür; Şimşek Yavuz, Serap; Turhan, Özge; Yıldırmak, Mustafa Taner; Köksal, İftihar; Taşova, Yeşim; Korten, Volkan; Yılmaz, Gürdal; Çelen, Mustafa Kemal; Altın, Sedat; Çelik, İlhami; Bayındır, Yaşar; Karaoğlan, İlkay; Yılmaz, Aydın; Özkul, Aykut; Gür, Hazal; Unal, Serhat; Kayaaslan, Bircan; Hasanoğlu, İmran; Dalkıran, Ayça; Aydos, Ömer; Çınar, Güle; Akdemir-Kalkan, İrem; İnkaya, Ahmet Çağkan; Aydin, Mehtap; Çakir, Hatice; Yıldız, Jale; Kocabıyık, Özenir; Arslan, Sonay; Nallı, Bayram; Demir, Ömer; Singil, Sarp; Ataman-Hatipoğlu, Çiğdem; Tuncer-Ertem, Günay; Kınıklı, Sami; Önal, Uğur; Mete, Bilgül; Dalgan, Gözde; Taşbakan, Meltem; Yamazhan, Tansu; Kömürcüoğlu, Berna; Yalnız, Enver; Benli, Aysun; Keskin-Sarıtaş, Çağla; Ertosun, Mustafa Gökhan; Özkan, Özlenen; Emre, Salih; Arıca, Seçil; Kuşçu, Ferit; Candevir, Aslıhan; Ertürk-Şengel, Buket; Ayvaz, Fadime; Aksoy, Firdevs; Mermutluoğlu, Çiğdem; Demir, Yakup; Günlüoğlu, Gülşah; Tural-Önür, Seda; Kılıç-Toker, Ayşin; Eren, Esma; Otlu, Barış; Mete, Ayşe Özlem; Koçak, Kübra; Ateş, Hale; Koca-Kalkan, İlkay; Aksu, Kurtuluş
Source
The Lancet; July 2021, Vol. 398 Issue: 10296 p213-222, 10p
Subject
Language
ISSN
01406736; 1474547X
Abstract
CoronaVac, an inactivated whole-virion SARS-CoV-2 vaccine, has been shown to be well tolerated with a good safety profile in individuals aged 18 years and older in phase 1/2 trials, and provided a good humoral response against SARS-CoV-2. We present the interim efficacy and safety results of a phase 3 clinical trial of CoronaVac in Turkey.