학술논문
Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial
Document Type
Article
Author
Villar, Jesús; Ferrando, Carlos; Martínez, Domingo; Ambrós, Alfonso; Muñoz, Tomás; Soler, Juan A; Aguilar, Gerardo; Alba, Francisco; González-Higueras, Elena; Conesa, Luís A; Martín-Rodríguez, Carmen; Díaz-Domínguez, Francisco J; Serna-Grande, Pablo; Rivas, Rosana; Ferreres, José; Belda, Javier; Capilla, Lucía; Tallet, Alec; Añón, José M; Fernández, Rosa L; González-Martín, Jesús M; Aguilar, Gerardo; Alba, Francisco; Álvarez, Julián; Ambrós, Alfonso; Añón, José M.; Asensio, María J.; Belda, Javier; Blanco, Jesús; Blasco, Marisa; Cachafeiro, Lucia; del Campo, Rafael; Capilla, Lucía; Carbonell, José A.; Carbonell, Nieves; Cariñena, Agustín; Carriedo, Demetrio; Chico, Mario; Conesa, Luís A.; Corpas, Ruth; Cuervo, Javier; Díaz-Domínguez, Francisco J.; Domínguez-Antelo, Cristina; Fernández, Lorena; Fernández, Rosa L.; Ferrando, Carlos; Ferreres, José; Gamboa, Eneritz; González-Higueras, Elena; González-Luengo, Raúl I.; González-Martín, Jesús M.; Martínez, Domingo; Martín-Rodríguez, Carmen; Muñoz, Tomás; Ortiz Díaz-Miguel, Ramón; Pérez-González, Raquel; Prieto, Ana M.; Prieto, Isidro; Rivas, Rosana; Rojas-Viguera, Leticia; Romera, Miguel A.; Sánchez-Ballesteros, Jesús; Segura, José M.; Serna-Grande, Pablo; Serrano, Ainhoa; Solano, Rosario; Soler, Juan A.; Soro, Marina; Tallet, Alec; Villar, Jesús
Source
The Lancet Respiratory Medicine; March 2020, Vol. 8 Issue: 3 p267-276, 10p
Subject
Language
ISSN
22132600; 22132619
Abstract
There is no proven specific pharmacological treatment for patients with the acute respiratory distress syndrome (ARDS). The efficacy of corticosteroids in ARDS remains controversial. We aimed to assess the effects of dexamethasone in ARDS, which might change pulmonary and systemic inflammation and result in a decrease in duration of mechanical ventilation and mortality.