학술논문
Personalised mechanical ventilation tailored to lung morphology versus low positive end-expiratory pressure for patients with acute respiratory distress syndrome in France (the LIVE study): a multicentre, single-blind, randomised controlled trial
Document Type
Article
Author
Constantin, Jean-Michel; Jabaudon, Matthieu; Lefrant, Jean-Yves; Jaber, Samir; Quenot, Jean-Pierre; Langeron, Olivier; Ferrandière, Martine; Grelon, Fabien; Seguin, Philippe; Ichai, Carole; Veber, Benoit; Souweine, Bertrand; Uberti, Thomas; Lasocki, Sigismond; Legay, François; Leone, Marc; Eisenmann, Nathanael; Dahyot-Fizelier, Claire; Dupont, Hervé; Asehnoune, Karim; Sossou, Achille; Chanques, Gérald; Muller, Laurent; Bazin, Jean-Etienne; Monsel, Antoine; Borao, Lucile; Garcier, Jean-Marc; Rouby, Jean-Jacques; Pereira, Bruno; Futier, Emmanuel; Sophie, Cayot; Thomas, Godet; Renaud, Guerin; Camille, Verlac; Russel, Chabanne; Bernard, Cosserant; Raiko, Blondonnet; Alexandre, Lautrette; Nathanael, Eisenmann; Laurent, Muller; Pablo, Massanet; Caroline, Boutin; Saber, Barbar; Claire, Roger; Fouad, Belafia; Moussa, Cisse; Marion, Monnin; Matthieu, Conseil; Julie, Carr; Audrey, De Jong; Auguste, Dargent; Pascal, Andreu; Thomas, Lebouvrier; Yoann, Launey; Antoine, Roquilly; Raphael, Cinotti; Caroline, Boutin; Anne-Charlotte, Tellier; Mathilde, Barbaz; Benjamin, Cohen; Edouard, Lemarche; Pierre-Marie, Bertrand; Charlotte, Arberlot; Laurent, Zieleskiewicz; Emmanuelle, Hammad; Garry, Duclos; Calypso, Mathie; Herve, Dupont; Benoit, Veber; Jean-Christophe, Orban; Hervé, Quintard; Thomas, Rimmele; Julien, Crozon-Clauzel; Marinne, Le Core; Fabien, Grelon; Mona, Assefi; Frank, Petitas; Jerome, Morel; Serge, Molliex; Nanadougmar, Hadanou
Source
The Lancet Respiratory Medicine; October 2019, Vol. 7 Issue: 10 p870-880, 11p
Subject
Language
ISSN
22132600; 22132619
Abstract
The effect of personalised mechanical ventilation on clinical outcomes in patients with acute respiratory distress syndrome (ARDS) remains uncertain and needs to be evaluated. We aimed to test whether a mechanical ventilation strategy that was personalised to individual patients' lung morphology would improve the survival of patients with ARDS when compared with standard of care.