부산대학교 도서관

From January 1983 through August 1983, 18 children were identified with KS in Denver, CO. An epidemiologic questionnaire was administered to 14 families and to 10 "best friend" controls at a mean of 27 days after onset of illness (range 3-60 days). 39 samples of vacuumed house dust from homes frequented by 11 cases and 21 samples from 7 control homes were examined for mites using sieve filtration. IgG antibody to 2 species of mite was measured by ELIZA in convalescent sera from 12 patients and 10 similarly aged hospitalized controls. 8 of 14 KS patients reported an exposure to freshly cleaned rugs in the month prior to onset of KS. 6 of the 8 patients were exposed in locations outside of the home. 2 of 10 controls recalled carpet cleaning within their home in the previous 30 days and none reported exposure outside the home. There was no difference between cases and controls with regard to other housecleaning practices, pets, home humidification or air conditioning. Mite analysis revealed that 2 of 39 KS samples had mites in low concentrations (1/.05 gms) compared to 1 of 21 control samples. Mean anti-mite Ab was .196 and .212 in KS patients compared to .218 and .269 in controls for the two mite species tested. Although this study supports an association between exposure to cleaned carpets and KS, we were unable to demonstrate any correlation with mite exposure and KS. 82% of patients with KS in Denver had no mites demonstrable in homes which they frequented prior to illness.