학술논문
Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.
Document Type
Article
Author
Luke, Thomas; Hua Wu; Jincun Zhao; Channappanavar, Rudragouda; Coleman, Christopher M.; Jin-An Jiao; Hiroaki Matsushita; Ye Liu; Postnikova, Elena N.; Ork, Britini L.; Glenn, Gregory; Flyer, David; Defang, Gabriel; Raviprakash, Kanakatte; Kochel, Tadeusz; Jonathan Wang; Wensheng Nie; Smith, Gale; Hensley, Lisa E.; Olinger, Gene G.
Source
Science Translational Medicine; 2/17/2016, Vol. 8 Issue 326, p1-9, 9p
Subject
Language
ISSN
19466234
Abstract
The article discusses the study on the effectiveness of transchromosomic bovine human immunoglobulins G (Tc hIgG) purified from the plasma of animals that received MERS-CoV vaccine in neutralizing the virus. The study reportedly involved bovine that were selected for health and genetic characteristics. The results revealed that Tc hIgG inhibits MERS-CoV.