학술논문

Birth of piglets after transferring of in vitro-produced embryos pre-matured with R-roscovitine.
Document Type
Article
Source
Reproduction; Jun2005, Vol. 129 Issue 6, p747-755, 9p, 1 Diagram, 3 Charts, 1 Graph
Subject
HUMAN embryos
FERTILIZATION in vitro
GLUTATHIONE
MEIOSIS
CELL division
KARYOKINESIS
Language
ISSN
14701626
Abstract
Discusses a study to evaluate the nuclear maturation, the intracellular glutathione content, the normality of fertilization and full development after transplantation of embryos derived from precultured porcine oocytes. Collection of the oocytes at the germinal vesicle; Progress of roscovitine-treated oocytes through meiosis to the metaphase stage in a step-wise in vitro maturation program; Importance of validation before the introduction of rascovitine into routine procedures.