학술논문

Embracing the complexity of pre-mRNA splicing.
Document Type
Article
Source
Cell Research; Aug2010, Vol. 20 Issue 8, p866-868, 3p
Subject
MESSENGER RNA
RNA splicing
CANCER
EXONS (Genetics)
GENETIC disorders
GENETIC mutation
Language
ISSN
10010602
Abstract
The article presents information on the complications associated with splicing of pre-messenger RNA. Any kind of flaw in the RNA splicing process can lead to genetic disorders in humans and these mutations later cause different kinds of cancers. It also discusses a "splicing code", which distinguishes the exons spliced alternatively from the exons spliced constitutively.