학술논문

Modification of the Ferret Model for Pneumonia From Seasonal Human Influenza A Virus Infection.
Document Type
Article
Source
Veterinary Pathology; May2012, Vol. 49 Issue 3, p562-568, 7p
Subject
ANIMAL models in research
FERRET
IMMUNOHISTOCHEMISTRY
LUNGS
PATHOLOGY
Language
ISSN
03009858
Abstract
The article provides information on a study which established a model of human seasonal influenza virus infection that consistently induces pneumonia in ferrets. The study made use of an intra-tracheal route of inoculation and a high viral dose of 109TCID50. It also tested these modified experimental procedures for subtypes H1N1 and H3N2 and for recent and older strains of these subtypes.